From the Maker of MIGRANAL® and Authorized Generic MIGRANAL® (dihydroergotamine mesylate)

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INDICATION

MIGRANAL ® (dihydroergotamine mesylate) Nasal Spray is used to treat an active migraine headache with or without aura. Do not use it to try to prevent a migraine if you have no symptoms, to treat a common tension headache, or to treat a migraine that is not typical of your usual migraine.

IMPORTANT SAFETY INFORMATION

Serious or potentially life-threatening reductions in blood flow to the brain or extremities due to interactions between dihydroergotamine (the active ingredient in MIGRANAL Nasal Spray) and protease inhibitors and macrolide antibiotics have been reported rarely. As a result, these medications should not be taken together.

Please click here for full Prescribing Information, including Boxed Warning and Patient Information.

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IMPORTANT SAFETY INFORMATION (continued)

Do not use MIGRANAL Nasal Spray if you:
Before taking MIGRANAL Nasal Spray, tell your doctor if:

The use of MIGRANAL Nasal Spray should not exceed dosing guidelines and should not be used on a daily basis.

Serious cardiac (heart) events, including some that have been fatal, have occurred following use of injectable dihydroergotamine, the active ingredient in MIGRANAL Nasal Spray, but are extremely rare.

You may experience some nasal congestion or irritation, altered sense of taste, sore throat, nausea, vomiting, dizziness, and fatigue after using MIGRANAL Nasal Spray. Contact your doctor immediately if you experience:

You are encouraged to report adverse side effects of prescription drugs to Bausch Health US, LLC at 1-800-321-4576 or the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please click here for full Prescribing Information, including Boxed Warning and Patient Information.


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